In vitro studies for the antiparasitic activities of Azadirachta indica extract

Coccidiosis and helminthiasis are two parasitic diseases that harm both health the economy. The present study aimed to assess effect of Azadirachta indica leaf extracts (AILE) as an anti-parasitic modulator during murine coccidiosis well helminthic infection. Phytochemical analysis using FT-IR showed presence eleven compounds. A dose-dependent efficacy was observed in all experiments. At highest concentration (200 mg/mL), time consumed induce paralysis death for worms recorded at 9.329 ± 2.183 10.024 1.542 min, respectively. Histological revealed conspicuous deformity surface architecture treated worms. SEM also cuticular shrinkage body In vitro incubation with AILE (100 mg/mL) 96 hr inhibited sporulation by approximately 60%. (50 25 amprolium, DettolTM, phenol, formalin-induced variable inhibition levels 28%, 44%, 37.33%, 81.33%, 89.33%, 0% addition, IC50 obtained 66.214 µg/mL a percentage antioxidant activity be 74.76 2.23. Our results indicate exhibits powerful anthelmintic anticoccidial activities it could exploited further development novel therapeutic agent.